Bladder Exstrophy


Exstrophy means ‘turned inside out’. Bladder exstrophy is a congenital (present at birth) abnormality of the bladder. It happens when the skin over the lower abdominal wall (bottom part of the tummy) does not form properly, so the bladder is open and exposed on the outside of the abdomen.

Conditions we treat

Treatment Options we offer 

The Kelly Procedure

The Kelly Procedure is a novel surgical technique performed at GOSH by Prof. Imran Mushtaq and his colleagues when children present with bladder exstrophy – a very rare condition that affects 1 out of 50,000 births. GOSH is one of only 3 Children’s Hospitals in the world that are considered to be world-leading experts in treating this rare condition. The biggest challenge for these children is in achieving good bladder control and the Kelly has been shown to have better outcomes compared to other techniques. We have performed more than 300 such operations in children with bladder exstrophy in the past 15 years.

Nephron sparing surgery

As well as The Kelly Procedure, Prof Imran Mushtaq and his surgical colleagues at GOSH have also mastered a surgical technique known as Nephron Sparing Surgery, where surgeons remove just the tumour from the kidney and leave the rest of the kidney in place. This avoids taking out the whole kidney and is helpful for children that have a genetic predisposition to Wilm’s tumour and therefore likely to develop further tumours. Nephron sparing surgery means that we can preserve as much kidney tissue as is possible and this reduces the chance that the child will require kidney dialysis and kidney transplantation.

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Professor Imran Mushtaq

Consultant Paediatric Urologist

Professor Imran Mushtaq, Consultant Paediatric Urologist at Great Ormond Street Hospital (GOSH) and Senior Lecturer at the Institute of Child Health, London, started his career as a Paediatric Urologist in 2001.

He pioneered minimally invasive urological surgery in London and is widely regarded as one of the leading laparoscopic surgeons in the UK, with expertise in the techniques of nephrectomy, partial nephrectomy, adrenalectomy, pyeloplasty and robotic surgery. Professor Mushtaq has a specialist interest in reconstructive urology, comprising hypospadias, disorders of sex development, neuropathic bladder and bladder exstrophy and epispadias. GOSH is the only institution in the UK that manages children with bladder exstrophy, for which the hospital has exceptional expertise and offers cutting-edge treatment.

Professor Mushtaq is a member of the review board of many prestigious journals. He has published more than 50 scientific articles in national and international indexed journals, presented over 30 abstracts, and authored 10 book chapters.
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